Compile Data Set for Download or QSAR

Found 40 hits of Enzyme Inhibition Constant Data   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064015(7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...)copy SMILEScopy InChI
Affinity DataKi:  90nMAssay Description:Inhibitory activity against L-arginine binding to Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064015(7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064018(7-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064015(7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064011(7-Butyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064018(7-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064015(7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064011(7-Butyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human nNeuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatogra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064018(7-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064010(3-Ethyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064011(7-Butyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50049257(Azepan-(2Z)-ylideneamine | CHEMBL315857 | CHEMBL54...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064013(7-(2-Ethyl-butyl)-azepan-(2Z)-ylideneamine; hydroc...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064010(3-Ethyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory activity evaluated from soluble cell extract of Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatographyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064013(7-(2-Ethyl-butyl)-azepan-(2Z)-ylideneamine; hydroc...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50049257(Azepan-(2Z)-ylideneamine | CHEMBL315857 | CHEMBL54...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064010(3-Ethyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064014((R)-6-Methyl-azepan-(2Z)-ylideneamine; hydrochlori...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human nNeuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatogra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064013(7-(2-Ethyl-butyl)-azepan-(2Z)-ylideneamine; hydroc...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064019(5-Methyl-azepan-(2Z)-ylideneamine; hydrochloride |...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064012(3-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064017(7-Phenyl-azepan-(2Z)-ylideneamine; hydrochloride |...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064014((R)-6-Methyl-azepan-(2Z)-ylideneamine; hydrochlori...)copy SMILEScopy InChI
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064015(7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human endothelia constitutive enzyme (Endothelial nitric oxide synthase) and partially pur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064019(5-Methyl-azepan-(2Z)-ylideneamine; hydrochloride |...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity evaluated from soluble cell extract of Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatographyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064017(7-Phenyl-azepan-(2Z)-ylideneamine; hydrochloride |...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50049257(Azepan-(2Z)-ylideneamine | CHEMBL315857 | CHEMBL54...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human endothelia constitutive enzyme (Endothelial nitric oxide synthase) and partially pur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064012(3-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory activity evaluated from soluble cell extract of Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatographyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064012(3-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064018(7-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human endothelia constitutive enzyme (Endothelial nitric oxide synthase) and partially pur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064019(5-Methyl-azepan-(2Z)-ylideneamine; hydrochloride |...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+4nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064017(7-Phenyl-azepan-(2Z)-ylideneamine; hydrochloride |...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064010(3-Ethyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human endothelia constitutive enzyme (Endothelial nitric oxide synthase) and partially pur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064014((R)-6-Methyl-azepan-(2Z)-ylideneamine; hydrochlori...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human endothelia constitutive enzyme (Endothelial nitric oxide synthase) and partially pur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064019(5-Methyl-azepan-(2Z)-ylideneamine; hydrochloride |...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human endothelia constitutive enzyme (Endothelial nitric oxide synthase) and partially pur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50049257(Azepan-(2Z)-ylideneamine | CHEMBL315857 | CHEMBL54...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+4nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064011(7-Butyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human endothelia constitutive enzyme (Endothelial nitric oxide synthase) and partially pur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064017(7-Phenyl-azepan-(2Z)-ylideneamine; hydrochloride |...)copy SMILEScopy InChI
Affinity DataIC50: 2.15E+5nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human endothelia constitutive enzyme (Endothelial nitric oxide synthase) and partially pur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064012(3-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+5nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human endothelia constitutive enzyme (Endothelial nitric oxide synthase) and partially pur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50064013(7-(2-Ethyl-butyl)-azepan-(2Z)-ylideneamine; hydroc...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+5nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human endothelia constitutive enzyme (Endothelial nitric oxide synthase) and partially pur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348M29PubMed
* indicates data uncertainty>20%