Compile Data Set for Download or QSAR

Found 19 hits of Enzyme Inhibition Constant Data   

TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066417(CHEMBL112806 | N-(4-Benzyloxy-phenyl)-N'-(4-tert-b...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066427(CHEMBL109210 | N,N'-Bis-(4-butyl-phenyl)-guanidine)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066420(CHEMBL112132 | N-(4-Benzyloxy-phenyl)-N'-(4-butyl-...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066423(CHEMBL326502 | N,N'-Bis-(4-butoxy-phenyl)-guanidin...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066425(CHEMBL112515 | N,N'-Bis-(4-phenoxy-phenyl)-guanidi...)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50010754(CHEMBL81626 | N,N'-Bis-(4-isopropyl-phenyl)-guanid...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066428(CHEMBL326774 | N-Acenaphthen-5-yl-N'-(4-sec-butyl-...)copy SMILEScopy InChI
Affinity DataIC50: 680nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066057(CHEMBL110909 | CHEMBL320199 | N,N'-Bis-(4-sec-buty...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066419(CHEMBL326741 | N,N'-Bis-(4-hexyl-phenyl)-guanidine)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066424(CHEMBL331126 | N,N'-Bis-(4-phenylsulfanyl-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 840nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066422(CHEMBL326130 | N,N'-Bis-biphenyl-4-yl-guanidine)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50010736(CHEMBL78083 | N,N'-Bis-(4-ethyl-phenyl)-guanidine)copy SMILEScopy InChI
Affinity DataIC50: 1.39E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066421(CHEMBL320340 | N,N'-Bis-(4-tert-butyl-phenyl)-guan...)copy SMILEScopy InChI
Affinity DataIC50: 1.54E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066068(CHEMBL28853 | N-Acenaphthen-5-yl-N'-(4-methoxy-nap...)copy SMILEScopy InChI
Affinity DataIC50: 1.64E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066429(CHEMBL325215 | N-(4-Butoxy-phenyl)-N'-[4-(4-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 1.78E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066430(2-(4-Methyl-piperazin-1-yl)-5-(2,3,5-trichloro-phe...)copy SMILEScopy InChI
Affinity DataIC50: 2.55E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM30705(CHEMBL744 | MLS000069369 | RILUZOLE | SMR000058231...)copy SMILEScopy InChI
Affinity DataIC50: 4.73E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066426(CHEMBL114716 | N,N'-Bis-[4-(4-hydroxy-butyl)-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 8.19E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50010743(N,N'-Di-p-tolyl-guanidine)copy SMILEScopy InChI
Affinity DataIC50: 9.21E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
* indicates data uncertainty>20%