Compile Data Set for Download or QSAR

Found 26 hits of Enzyme Inhibition Constant Data   

TargetEndothelin-1 receptor(RAT)
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069575(3-Benzo[1,2,5]thiadiazol-5-yl-5-hydroxy-5-(4-metho...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin-1 receptor(RAT)
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50034267(3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methox...)copy SMILEScopy InChI
Affinity DataIC50: 0.440nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin-1 receptor(RAT)
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069569(5-Dimethylamino-naphthalene-1-sulfonic acid benzo[...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin-1 receptor(RAT)
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069571(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]thiadiazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin-1 receptor(RAT)
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069573(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]thiadiazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin-1 receptor(RAT)
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069565(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin-1 receptor(RAT)
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069566(3-(4-Methoxy-phenyl)-1-(6-methyl-benzo[1,2,5]thiad...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin-1 receptor(RAT)
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069570(1-Benzo[1,2,5]thiadiazol-5-ylmethyl-3-(4-methoxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin-1 receptor(RAT)
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069567(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069572(1-Benzo[1,2,5]thiadiazol-5-ylmethyl-4-(4-methoxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50034267(3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methox...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069566(3-(4-Methoxy-phenyl)-1-(6-methyl-benzo[1,2,5]thiad...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069575(3-Benzo[1,2,5]thiadiazol-5-yl-5-hydroxy-5-(4-metho...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin-1 receptor(RAT)
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069564(5-Dimethylamino-naphthalene-1-sulfonic acid benzo[...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin-1 receptor(RAT)
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069572(1-Benzo[1,2,5]thiadiazol-5-ylmethyl-4-(4-methoxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069568(1-Benzo[1,3]dioxol-5-ylmethyl-4-(4-methoxy-phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069565(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069570(1-Benzo[1,2,5]thiadiazol-5-ylmethyl-3-(4-methoxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin-1 receptor(RAT)
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069568(1-Benzo[1,3]dioxol-5-ylmethyl-4-(4-methoxy-phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069571(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]thiadiazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069573(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]thiadiazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069567(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin-1 receptor(RAT)
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069574(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]oxadiazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069574(3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]oxadiazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069564(5-Dimethylamino-naphthalene-1-sulfonic acid benzo[...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Merck KGaA

Curated by ChEMBL
LigandPNGBDBM50069569(5-Dimethylamino-naphthalene-1-sulfonic acid benzo[...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5Z9HPubMed
* indicates data uncertainty>20%