Compile Data Set for Download or QSAR

Found 11 hits of Enzyme Inhibition Constant Data   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM81987(CHEMBL116048 | McN-5652-15)copy SMILEScopy InChI
Affinity DataKi:  0.0100nMAssay Description:In vitro binding affinity of the compound against Serotonin transporter (SERT) from LLC-PK1 cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3DJNPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50073436((2-(2-((dimethylamino)methyl)phenylthio)-5-iodophe...)copy SMILEScopy InChI
Affinity DataKi:  0.0970nMAssay Description:In vitro binding affinity of the compound against Serotonin transporter (SERT) from LLC-PK1 cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3DJNPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50073438(CHEMBL278165 | [5-Bromo-2-(2-dimethylaminomethyl-p...)copy SMILEScopy InChI
Affinity DataKi:  0.520nMAssay Description:In vitro binding affinity of the compound against Serotonin transporter (SERT) from LLC-PK1 cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3DJNPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM81987(CHEMBL116048 | McN-5652-15)copy SMILEScopy InChI
Affinity DataKi:  1.82nMAssay Description:Compound was tested for inhibiting reuptake of [3H]- NE by norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3DJNPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM81987(CHEMBL116048 | McN-5652-15)copy SMILEScopy InChI
Affinity DataKi:  11.3nMAssay Description:In vitro binding affinity of the compound against monoamine transporter NET (norepinephrine transporter) in LLC-PK1 cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3DJNPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM81987(CHEMBL116048 | McN-5652-15)copy SMILEScopy InChI
Affinity DataKi:  23.5nMAssay Description:Concentration of the compound inhibiting Dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3DJNPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50073438(CHEMBL278165 | [5-Bromo-2-(2-dimethylaminomethyl-p...)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:In vitro binding affinity of the compound against monoamine transporter NET (norepinephrine transporter) in LLC-PK1 cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3DJNPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM81987(CHEMBL116048 | McN-5652-15)copy SMILEScopy InChI
Affinity DataKi:  112nMAssay Description:In vitro binding affinity of the compound against Dopamine transporter in LLC-PK1 cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3DJNPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50073436((2-(2-((dimethylamino)methyl)phenylthio)-5-iodophe...)copy SMILEScopy InChI
Affinity DataKi:  234nMAssay Description:In vitro binding affinity of the compound against monoamine transporter NET (norepinephrine transporter) in LLC-PK1 cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3DJNPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50073436((2-(2-((dimethylamino)methyl)phenylthio)-5-iodophe...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity of the compound against Dopamine transporter in LLC-PK1 cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3DJNPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50073438(CHEMBL278165 | [5-Bromo-2-(2-dimethylaminomethyl-p...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity of the compound against Dopamine transporter in LLC-PK1 cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3DJNPubMed
* indicates data uncertainty>20%