Reaction Details  Report a problem with these data
Cell Reactant:
Flavin reductase (NADPH)
Syringe Reactant:
BDBM38549
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
10/06/23
ΔG°:
-7.85±0.1 (kcal/mole)
Temperature:
298.15±0 (K)
ΔH° :
-6.77±0.13 (kJ/mole)
ΔS° :
0±0 (kJ/mole-K)
Citation
 Ryu, K; Kim, M; Griesinger, C; Lee, D Method of increasing platelet counts of a subject US Patent  US11744839 Publication Date 9/5/2023
Cell React
Name:
Flavin reductase (NADPH)
Synonyms:
1.3.1.24 | 1.5.1.30 | BLVRB | BLVRB_HUMAN | BVR-B | Biliverdin reductase B | Biliverdin-IX beta-reductase | FLR
Type:
PROTEIN
Mol. Mass.:
22123.63
Organism:
Homo sapiens
Description:
ChEMBL_100283
Residue:
206
Sequence:
MAVKKIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHVVVGDVLQAADVDKTVAGQDAVIVLLGTRNDLSPTTVMSEGARNIVAAMKAHGVDKVVACTSAFLLWDPTKVPPRLQAVTDDHIRMHKVLRESGLKYVAVMPPHIGDQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTDEYDGHSTYPSHQYQ
  
Syringe React
Name:
BDBM38549
Synonyms:
2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazino]ethoxy]ethanol | 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]-1-piperazinyl]ethoxy]ethanol | 4-[(3-carboxy-2-hydroxy-1-naphthalenyl)methyl]-3-hydroxy-2-naphthalenecarboxylic acid | 4-[(3-carboxy-2-hydroxy-1-naphthyl)methyl]-3-hydroxy-2-naphthoic acid | CHEMBL170358 | CHEMBL177880 | HYDROXYZINE PAMOATE | MLS000028605 | Pamoic acid | SMR000058728 | US11744839, Compound of formula 8 | cid_25096
Type:
Small organic molecule
Emp. Form.:
C23H16O6
Mol. Mass.:
388.3695
SMILES:
OC(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc23)C(O)=O)c1O
Structure:
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