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Target
Somatostatin receptor type 2
Ligand
BDBM527739
Substrate
n/a
Meas. Tech.
cAMP Assay of SSTR2
EC50
0.55±n/a nM
Citation
 Han, S; Kim, SH; Zhu, Y Somatostatin modulators and uses thereof US Patent  US11186590 Publication Date 11/30/2021
Target
Name:
Somatostatin receptor type 2
Synonyms:
SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2)
Type:
Enzyme
Mol. Mass.:
41344.94
Organism:
Homo sapiens (Human)
Description:
P30874
Residue:
369
Sequence:
MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
  
Inhibitor
Name:
BDBM527739
Synonyms:
US11186590, Compound 3-3
Type:
Small organic molecule
Emp. Form.:
C25H23F3N6O
Mol. Mass.:
480.4849
SMILES:
Nc1ncc(-c2cccc(F)c2)c(N2CC[C@@H]3NCCO[C@H]3C2)c1-c1nc2cc(F)cc(F)c2[nH]1 |r|
Structure:
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