Target
Bromodomain testis-specific protein [22-138]
Ligand
BDBM543795
Substrate
n/a
Meas. Tech.
AlphaLisa Assay
IC50
194±n/a nM
Citation
 Upadhayaya, RSKethiri, RMadan, SRajaiah, SK Fused pyrimidine compounds as BRD4 and JAK2 dual inhibitors and methods for use thereof US Patent  US11279703 Publication Date 3/22/2022
Target
Name:
Bromodomain testis-specific protein [22-138]
Synonyms:
BRDT | BRDT_HUMAN | Bromodomain testis-specific protein (BRDT)(BD1)
Type:
n/a
Mol. Mass.:
13948.58
Organism:
Homo sapiens (Human)
Description:
Q58F21[22-138]
Residue:
117
Sequence:
TKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQ
  
Inhibitor
Name:
BDBM543795
Synonyms:
US11279703, TABLE 6.385 | US11279703, TABLE 6.386
Type:
Small organic molecule
Emp. Form.:
C27H30FN7O3S
Mol. Mass.:
551.636
SMILES:
CC(C)(C)S(=O)(=O)Nc1cccc(c1)-n1ccc2cnc(Nc3ccc(C(=O)N4CCNCC4)c(F)c3)nc12
Structure:
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