Reaction Details  Report a problem with these data
Target
Bromodomain testis-specific protein [22-138]
Ligand
BDBM550492
Substrate
n/a
Meas. Tech.
ATPLITE assay
IC50
133±n/a nM
Citation
 Bradner, JE; Qi, J; Tanaka, M; Buckley, D Cyano thienotriazolodiazepines and uses thereof US Patent  US11306105 Publication Date 4/19/2022
Target
Name:
Bromodomain testis-specific protein [22-138]
Synonyms:
BRDT | BRDT_HUMAN | Bromodomain testis-specific protein (BRDT)(BD1)
Type:
n/a
Mol. Mass.:
13948.58
Organism:
Homo sapiens (Human)
Description:
Q58F21[22-138]
Residue:
117
Sequence:
TKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQ
  
Inhibitor
Name:
BDBM550492
Synonyms:
US11306105, Compound 108
Type:
Small organic molecule
Emp. Form.:
C23H24N6O2S
Mol. Mass.:
448.541
SMILES:
C[C@@H](O)CNC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(cc1)C#N |r,c:9|
Structure:
Search PDB for entries with ligand similarity: