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Target
Bromodomain-containing protein 9 [133-239]
Ligand
BDBM565284
Substrate
n/a
Meas. Tech.
Bromodomain TR-FRET Competition Binding Assay
IC50
<10±n/a nM
Citation
 Ruppel, SK; Yang, Z; Lowe, JT; Voigt, JH; Netherton, M Compounds and uses thereof US Patent  US11414416 Publication Date 8/16/2022
Target
Name:
Bromodomain-containing protein 9 [133-239]
Synonyms:
BRD9 | BRD9_HUMAN | Bromodomain-containing protein 9 (BRD9)(133-239)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12383.34
Organism:
Homo sapiens (Human)
Description:
aa 133-239
Residue:
107
Sequence:
PAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSK
  
Inhibitor
Name:
BDBM565284
Synonyms:
US11414416, Compound D33 | US11560381, Compound D33 | piperazin-1-yl)-4-oxobutoxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Type:
Small organic molecule
Emp. Form.:
C39H40N6O9
Mol. Mass.:
736.7697
SMILES:
COc1cc(cc(OC)c1CN1CCN(CC1)C(=O)CCCOc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12)-c1cn(C)c(=O)c2cnccc12
Structure:
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