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Target
Calcium/calmodulin-dependent protein kinase type 1D
Ligand
BDBM585224
Substrate
n/a
Meas. Tech.
Biochemical CaMK1D Enzymatic Activity Assay
IC50
24.0±n/a nM
Citation
 Fischer, P; Fromont, C; Stevenson, B; Butterworth, S; Iacobini, G; Greco, G; Sanz, MG; Jones, H; Kaur, D Kinase inhibitors US Patent  US11530193 Publication Date 12/20/2022
Target
Name:
Calcium/calmodulin-dependent protein kinase type 1D
Synonyms:
CAMK1D | CAMKID | CaM kinase I delta | KCC1D_HUMAN
Type:
PROTEIN
Mol. Mass.:
42916.83
Organism:
Homo sapiens (Human)
Description:
ChEMBL_586559
Residue:
385
Sequence:
MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKDCLAPSTLCSFISSSSGVSGVGAERRPRPTTVTAVHSGSK
  
Inhibitor
Name:
BDBM585224
Synonyms:
US11530193, Example 138
Type:
Small organic molecule
Emp. Form.:
C21H31N7O2
Mol. Mass.:
413.5165
SMILES:
CC(C)c1cc(Nc2nc(ncc2C(N)=O)N2C[C@@H](N)C[C@@H](O)C2)cc(n1)C(C)C |r|
Structure:
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