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Target
Leukotriene C4 synthase
Ligand
BDBM309977
Substrate
n/a
Meas. Tech.
In Vitro hLTC4 Synthase Enzyme Assay
IC50
47.0±n/a nM
Citation
 Ronn, R; Lindh, CJ; Ringberg, E; Andersson, HB; Nilsson, P; Schaal, WR; Munck af Rosenschöld, M; Nikitidis, A; Nikitidis, G; Johannesson, P; Tyrchan, C Compounds and uses US Patent  US9657001 Publication Date 5/23/2017
Target
Name:
Leukotriene C4 synthase
Synonyms:
LTC4 synthase | LTC4S | LTC4S_HUMAN | Leukotriene-C(4) synthase
Type:
PROTEIN
Mol. Mass.:
16575.59
Organism:
Homo sapiens (Human)
Description:
ChEMBL_961179
Residue:
150
Sequence:
MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVALAALGLLAHFLPAALRAALLGRLRTLLPWA
  
Inhibitor
Name:
BDBM309977
Synonyms:
US9657001, 6
Type:
Small organic molecule
Emp. Form.:
C24H26N2O4
Mol. Mass.:
406.4742
SMILES:
COc1cc(cnc1C(=O)C1CC1C(O)=O)N(CC1CC1)c1ccc2CCCc2c1
Structure:
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