Reaction Details  Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM601697
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
>10000±n/a nM
Citation
 Kristensen, JL; Jensen, AA; Märcher-Rørsted, E; Leth-Petersen, S 5-HT2A agonists for use in treatment of depression US Patent  US11642336 Publication Date 5/9/2023
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM601697
Synonyms:
US11642336, Compound 8
Type:
Small organic molecule
Emp. Form.:
C14H18F3NO2
Mol. Mass.:
289.2934
SMILES:
COc1cc(c(OC)cc1C1CCCNC1)C(F)(F)F
Structure:
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