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Target
Adenosine receptor A2a
Ligand
BDBM601697
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
1400±n/a nM
Citation
 Kristensen, JL; Jensen, AA; Märcher-Rørsted, E; Leth-Petersen, S 5-HT2A agonists for use in treatment of depression US Patent  US11642336 Publication Date 5/9/2023
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM601697
Synonyms:
US11642336, Compound 8
Type:
Small organic molecule
Emp. Form.:
C14H18F3NO2
Mol. Mass.:
289.2934
SMILES:
COc1cc(c(OC)cc1C1CCCNC1)C(F)(F)F
Structure:
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