Reaction Details  Report a problem with these data
Target
Bromodomain-containing protein 9 [133-239]
Ligand
BDBM621664
Substrate
n/a
Meas. Tech.
BRD9 Bromodomain TR-FRET Competition Binding Assay
IC50
55±n/a nM
Citation
 Zhou, Q; Bocker, M; Millan, DS; Chan, HM; Soares, L; Netherton, MR; Ruppel, SK; Yang, Z; Lowe, JT; Brucelle, F Methods and compounds for treating disorders US Patent  US11773085 Publication Date 10/3/2023
Target
Name:
Bromodomain-containing protein 9 [133-239]
Synonyms:
BRD9 | BRD9_HUMAN | Bromodomain-containing protein 9 (BRD9)(133-239)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12383.34
Organism:
Homo sapiens (Human)
Description:
aa 133-239
Residue:
107
Sequence:
PAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSK
  
Inhibitor
Name:
BDBM621664
Synonyms:
4-[4-[(dimethylamino)methyl]-3-(methylsulfanyl)phenyl]-2-methyl-1,2-dihydro-2,7-naphthyridin-1-one | US11773085, Compound B36
Type:
Small organic molecule
Emp. Form.:
C19H21N3OS
Mol. Mass.:
339.455
SMILES:
CSc1cc(ccc1CN(C)C)-c1cn(C)c(=O)c2cnccc12
Structure:
Search PDB for entries with ligand similarity: