Reaction Details  Report a problem with these data
Target
Bromodomain-containing protein 9 [133-239]
Ligand
BDBM621688
Substrate
n/a
Meas. Tech.
BRD9 Bromodomain TR-FRET Competition Binding Assay
IC50
55±n/a nM
Citation
 Zhou, Q; Bocker, M; Millan, DS; Chan, HM; Soares, L; Netherton, MR; Ruppel, SK; Yang, Z; Lowe, JT; Brucelle, F Methods and compounds for treating disorders US Patent  US11773085 Publication Date 10/3/2023
Target
Name:
Bromodomain-containing protein 9 [133-239]
Synonyms:
BRD9 | BRD9_HUMAN | Bromodomain-containing protein 9 (BRD9)(133-239)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12383.34
Organism:
Homo sapiens (Human)
Description:
aa 133-239
Residue:
107
Sequence:
PAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSK
  
Inhibitor
Name:
BDBM621688
Synonyms:
4-(4-((dimethylamino)methyl)-3,5-dimethoxyphenyl)-N,2-dimethyl-1-oxo-12-dihydroisoquinoline-6-carboxamide | US11773085, Compound B63
Type:
Small organic molecule
Emp. Form.:
C23H27N3O4
Mol. Mass.:
409.4782
SMILES:
CNC(=O)c1ccc2c(c1)c(cn(C)c2=O)-c1cc(OC)c(CN(C)C)c(OC)c1
Structure:
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