Reaction Details  Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM642622
Substrate
n/a
Meas. Tech.
Adenosine Receptor Binding Assay
Ki
>9400±n/a nM
Citation
 COHEN, CJ; KLUGE, AF; RAY, SS; HUTCHINSON, JH ADENOSINE ANALOGS FOR THE TREATMENT OF DISEASE US Patent  US20230416245 Publication Date 12/28/2023
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM642622
Synonyms:
US20230416245, Compound 60
Type:
Small organic molecule
Emp. Form.:
C15H17ClF2N4O2
Mol. Mass.:
358.771
SMILES:
Cc1c(Cl)nc2n(cnc2c1NCC(F)F)[C@@H]1[C@H]2C[C@H]2[C@@H](O)[C@H]1O |r|
Structure:
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