Reaction Details  Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM322996
Substrate
n/a
Meas. Tech.
cAMP Assay
EC50
515±n/a nM
Citation
 Grether, U; Nettekoven, M; Rogers-Evans, M; Schmitt, S; Stenton, BJ Triazolo[4,5-D]pyrimidines US Patent  US10183946 Publication Date 1/22/2019
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM322996
Synonyms:
4-[5-tert-butyl-3-[(1-methyltetrazol-5-yl)methyl]triazolo[4,5-d]pyrimidin-7-yl]-5-methyl-1,2-oxazole | US10183946, Example 27
Type:
Small organic molecule
Emp. Form.:
C15H18N10O
Mol. Mass.:
354.3698
SMILES:
Cc1oncc1-c1nc(nc2n(Cc3nnnn3C)nnc12)C(C)(C)C
Structure:
Search PDB for entries with ligand similarity: