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Target
Interleukin-2
Ligand
BDBM387294
Substrate
n/a
Meas. Tech.
Inhibition of IL-2 secretion
IC50
550±n/a nM
Citation
 Irlapati, NR; Deshmukh, GK; Karche, VP; Jachak, SM; Sinha, N; Palle, VP; Kamboj, RK Oxazoline and isoxazoline derivatives as CRAC modulators US Patent  US10292981 Publication Date 5/21/2019
Target
Name:
Interleukin-2
Synonyms:
IL-2 | IL2 | IL2_HUMAN | INN=Aldesleukin | Interleukin-2 | Interleukin-2 (IL-2) | T-cell growth factor | TCGF
Type:
Enzyme
Mol. Mass.:
17630.05
Organism:
Homo sapiens (Human)
Description:
P60568
Residue:
153
Sequence:
MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
  
Inhibitor
Name:
BDBM387294
Synonyms:
US10292981, Example 78
Type:
Small organic molecule
Emp. Form.:
C23H19ClN4O3
Mol. Mass.:
434.875
SMILES:
Cc1ccc(cc1-c1cnc(NC(=O)c2ccccc2Cl)cn1)C1=NOC(C)(C)C1=O |t:26|
Structure:
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