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Target
Dual specificity protein phosphatase 6
Ligand
BDBM35367
Substrate
n/a
Meas. Tech.
In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay
IC50
>50000±n/a nM
Citation
 PubChem, PC In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay PubChem Bioassay (2007)[AID]
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM35367
Synonyms:
(6-methyl-2,5-dihydropyrazolo[1,5-b][1,2,4]thiadiazol-2-yl)-phenyl-amine | 6-methyl-N-phenyl-2,5-dihydropyrazolo[1,5-b][1,2,4]thiadiazol-2-amine | MLS000037067 | SMR000037024 | cid_5293709
Type:
Small organic molecule
Emp. Form.:
C11H12N4S
Mol. Mass.:
232.305
SMILES:
Cc1cc2NC(Nc3ccccc3)Sn2n1
Structure:
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