Target
Beta-lactamase
Ligand
BDBM39813
Substrate
n/a
Meas. Tech.
Enzyme Inhibition Assay
pH
7±0
Ki
2.4e+2±n/a nM
Citation
 Caselli, EPowers, RABlasczcak, LCWu, CYPrati, FShoichet, BK Energetic, structural, and antimicrobial analyses of beta-lactam side chain recognition by beta-lactamases. Chem Biol 8:17-31 (2001) [PubMed]  Article
Target
Name:
Beta-lactamase
Synonyms:
AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC
Type:
Protien
Mol. Mass.:
41561.62
Organism:
Escherichia coli
Description:
P00811
Residue:
377
Sequence:
MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSIINGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNYPNPARVDAAWQILNALQ
  
Inhibitor
Name:
BDBM39813
Synonyms:
Acylglycineboronic acid, 12
Type:
Small organic molecule
Emp. Form.:
C3H7BClNO3
Mol. Mass.:
151.357
SMILES:
OB(O)CNC(=O)CCl
Structure:
Search PDB for entries with ligand similarity: