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Target
14-3-3 protein gamma
Ligand
BDBM39884
Substrate
n/a
Meas. Tech.
14-3-3 protein interaction modulators Dose Response Confirmation
IC50
>50000±n/a nM
Citation
 PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay (2007)[AID]
Target
Name:
14-3-3 protein gamma
Synonyms:
1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28289.17
Organism:
Homo sapiens (Human)
Description:
gi_21464101
Residue:
247
Sequence:
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
  
Inhibitor
Name:
BDBM39884
Synonyms:
5-(1H-indol-3-ylmethyl)-1,3-dimethyl-1,3-diazinane-2,4,6-trione | 5-(1H-indol-3-ylmethyl)-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione | 5-(1H-indol-3-ylmethyl)-1,3-dimethyl-barbituric acid | MLS000062601 | SMR000071137 | cid_2906351
Type:
Small organic molecule
Emp. Form.:
C15H15N3O3
Mol. Mass.:
285.2979
SMILES:
CN1C(=O)C(Cc2c[nH]c3ccccc23)C(=O)N(C)C1=O
Structure:
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