Reaction Details 
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Protein phosphatase 1 regulatory subunit 1A
Ligand
BDBM40783
Substrate
n/a
Meas. Tech.
Inhibition Assay
IC50
>1.0e+4±n/a nM
Citation
Wakimoto, T; Matsunaga, S; Takai, A; Fusetani, N Insight into binding of calyculin A to protein phosphatase 1: isolation of hemicalyculin a and chemical transformation of calyculin A. Chem Biol 9:309-19 (2002) [PubMed] ArticleMore Info.:
Target
Name:
Protein phosphatase 1 regulatory subunit 1A
Synonyms:
IPP1 | PPP1R1A | PPR1A_HUMAN | Protein phosphatase 1 regulatory subunit 1A (PP1) | Protein phosphatase inhibitor 1
Type:
Protein
Mol. Mass.:
19010.07
Organism:
Homo sapiens (Human)
Description:
Q13522
Residue:
171
Sequence:
MEQDNSPRKIQFTVPLLEPHLDPEAAEQIRRRRPTPATLVLTSDQSSPEIDEDRIPNPHLKSTLAMSPRQRKKMTRITPTMKELQMMVEHHLGQQQQGEEPEGAAESTGTQESRPPGIPDTEVESRLGTSGTAKKTAECIPKTHERGSKEPSTKEPSTHIPPLDSKGANSV
Inhibitor
Name:
BDBM40783
Synonyms:
C9/C35-calyculin (16)
Type:
Small organic molecule
Emp. Form.:
C23H45O12P
Mol. Mass.:
544.57
SMILES:
CO[C@@H](C[C@H](O)C(C)[C@H](O)C(C)CO)[C@H]1OC2(C[C@@H](O)[C@H](C)C(CCO)O2)C(C)(C)[C@H]1OP(O)(O)=O |r|
Structure:
