Reaction Details  Report a problem with these data
Target
Cathepsin G
Ligand
BDBM36955
Substrate
n/a
Meas. Tech.
Cathepsin G dose-response confirmation
IC50
1953.52±235.319 nM
Citation
 PubChem, PC Cathepsin G dose-response confirmation PubChem Bioassay (2008)[AID]
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM36955
Synonyms:
MLS000083777 | N-[(1S)-1-(5-benzylsulfonyl-1,3,4-oxadiazol-2-yl)-2-phenyl-ethyl]carbamic acid tert-butyl ester | N-[(1S)-2-phenyl-1-[5-(phenylmethyl)sulfonyl-1,3,4-oxadiazol-2-yl]ethyl]carbamic acid tert-butyl ester | SMR000047857 | cid_666554 | tert-butyl N-[(1S)-1-(5-benzylsulfonyl-1,3,4-oxadiazol-2-yl)-2-phenylethyl]carbamate | tert-butyl N-[(1S)-2-phenyl-1-[5-(phenylmethyl)sulfonyl-1,3,4-oxadiazol-2-yl]ethyl]carbamate
Type:
Small organic molecule
Emp. Form.:
C22H25N3O5S
Mol. Mass.:
443.516
SMILES:
CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)c1nnc(o1)S(=O)(=O)Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: