Reaction Details  Report a problem with these data
Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM41739
Substrate
n/a
Meas. Tech.
Dose Response Cell Based Assay for Agonists of the S1P2 Receptor of Purchased Analogues
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose Response Cell Based Assay for Agonists of the S1P2 Receptor of Purchased Analogues PubChem Bioassay (2007)[AID]
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM41739
Synonyms:
2,4-dimethyl-5-thiazolecarboxylic acid [2-[2,5-dimethyl-1-(phenylmethyl)-3-pyrrolyl]-2-oxoethyl] ester | 2,4-dimethylthiazole-5-carboxylic acid [2-(1-benzyl-2,5-dimethyl-pyrrol-3-yl)-2-keto-ethyl] ester | SR-01000759122-1 | [2-(1-benzyl-2,5-dimethylpyrrol-3-yl)-2-oxoethyl] 2,4-dimethyl-1,3-thiazole-5-carboxylate | [2-[2,5-dimethyl-1-(phenylmethyl)pyrrol-3-yl]-2-oxidanylidene-ethyl] 2,4-dimethyl-1,3-thiazole-5-carboxylate | cid_7469396
Type:
Small organic molecule
Emp. Form.:
C21H22N2O3S
Mol. Mass.:
382.476
SMILES:
Cc1nc(C)c(s1)C(=O)OCC(=O)c1cc(C)n(Cc2ccccc2)c1C
Structure:
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