Reaction Details  Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM46035
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
55300±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID]
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM46035
Synonyms:
2-(4-chloranyl-3-morpholin-4-ylsulfonyl-phenyl)-1,2-benzothiazol-3-one | 2-(4-chloro-3-morpholin-4-ylsulfonylphenyl)-1,2-benzothiazol-3-one | 2-(4-chloro-3-morpholinosulfonyl-phenyl)-1,2-benzothiazol-3-one | 2-[4-chloro-3-(4-morpholinylsulfonyl)phenyl]-1,2-benzothiazol-3-one | MLS-0315794.0001 | cid_2325813
Type:
Small organic molecule
Emp. Form.:
C17H15ClN2O4S2
Mol. Mass.:
410.895
SMILES:
Clc1ccc(cc1S(=O)(=O)N1CCOCC1)-n1sc2ccccc2c1=O
Structure:
Search PDB for entries with ligand similarity: