Reaction Details  Report a problem with these data
Target
Regulator of G-protein signaling 19
Ligand
BDBM47717
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao. PubChem Bioassay (2009)[AID]
Target
Name:
Regulator of G-protein signaling 19
Synonyms:
G protein signalling regulator 19 | GAIP | GNAI3IP | RGS19 | RGS19_HUMAN | Regulator of G-protein signaling 19 (RGS19)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24631.38
Organism:
Homo sapiens (Human)
Description:
gi_86990435
Residue:
217
Sequence:
MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA
  
Inhibitor
Name:
BDBM47717
Synonyms:
5-Ethylamino-anthra[1,9-cd]isoxazol-6-one | MLS000525596 | SMR000116070 | cid_776361
Type:
Small organic molecule
Emp. Form.:
C16H12N2O2
Mol. Mass.:
264.2787
SMILES:
CCNc1ccc2noc3-c4ccccc4C(=O)c1c23
Structure:
Search PDB for entries with ligand similarity: