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Target
Regulator of G-protein signaling 16
Ligand
BDBM47695
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID]
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47695
Synonyms:
2-(N-[2-(1-benzotriazolyl)-1-oxoethyl]-2-methoxyanilino)-N-(2-methylbutan-2-yl)-2-(1-methyl-2-pyrrolyl)acetamide | 2-(N-[2-(benzotriazol-1-yl)acetyl]-2-methoxyanilino)-N-(2-methylbutan-2-yl)-2-(1-methylpyrrol-2-yl)acetamide | 2-[(2-Benzotriazol-1-yl-acetyl)-(2-methoxy-phenyl)-amino]-N-(1,1-dimethyl-propyl)-2-(1-methyl-1H-pyrrol-2-yl)-acetamide | 2-[2-(benzotriazol-1-yl)ethanoyl-(2-methoxyphenyl)amino]-N-(2-methylbutan-2-yl)-2-(1-methylpyrrol-2-yl)ethanamide | MLS000074185 | N-tert-amyl-2-(N-[2-(benzotriazol-1-yl)acetyl]-2-methoxy-anilino)-2-(1-methylpyrrol-2-yl)acetamide | SMR000004342 | cid_646963
Type:
Small organic molecule
Emp. Form.:
C27H32N6O3
Mol. Mass.:
488.5814
SMILES:
CCC(C)(C)NC(=O)C(N(C(=O)Cn1nnc2ccccc12)c1ccccc1OC)c1cccn1C
Structure:
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