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Target
Regulator of G-protein signaling 16
Ligand
BDBM47698
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID]
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47698
Synonyms:
5-tert-butyl-3-[(2-chlorophenyl)methyl]-N-(2-morpholin-4-ylethyl)-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine | 5-tert-butyl-3-[(2-chlorophenyl)methyl]-N-(2-morpholin-4-ylethyl)triazolo[4,5-d]pyrimidin-7-amine | 5-tert-butyl-3-[(2-chlorophenyl)methyl]-N-[2-(4-morpholinyl)ethyl]-7-triazolo[4,5-d]pyrimidinamine | MLS000034072 | SMR000007885 | [5-tert-Butyl-3-(2-chloro-benzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-(2-morpholin-4-yl-ethyl)-amine | [5-tert-butyl-3-(2-chlorobenzyl)triazolo[4,5-d]pyrimidin-7-yl]-(2-morpholinoethyl)amine | cid_654918
Type:
Small organic molecule
Emp. Form.:
C21H28ClN7O
Mol. Mass.:
429.946
SMILES:
CC(C)(C)c1nc(NCCN2CCOCC2)c2nnn(Cc3ccccc3Cl)c2n1
Structure:
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