Reaction Details  Report a problem with these data
Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM41669
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
12000±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID]
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM41669
Synonyms:
4-[3-(4-chlorophenyl)-2-pyrazolin-1-yl]-N-[3-(dimethylamino)propyl]benzenesulfonamide | 4-[3-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]-N-[3-(dimethylamino)propyl]benzenesulfonamide | 4-[5-(4-chlorophenyl)-3,4-dihydropyrazol-2-yl]-N-[3-(dimethylamino)propyl]benzenesulfonamide | MLS000530254 | SMR000135230 | cid_2837694
Type:
Small organic molecule
Emp. Form.:
C20H25ClN4O2S
Mol. Mass.:
420.956
SMILES:
CN(C)CCCNS(=O)(=O)c1ccc(cc1)N1CCC(=N1)c1ccc(Cl)cc1 |c:20|
Structure:
Search PDB for entries with ligand similarity: