Reaction Details  Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM54703
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype
EC50
30000±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype PubChem Bioassay (2009)[AID]
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM54703
Synonyms:
1-(4-methoxyphenyl)-3-phenyl-2-propyn-1-one | 1-(4-methoxyphenyl)-3-phenyl-prop-2-yn-1-one | 1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-one | UNM-0000306061 | cid_616715
Type:
Small organic molecule
Emp. Form.:
C16H12O2
Mol. Mass.:
236.2653
SMILES:
COc1ccc(cc1)C(=O)C#Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: