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Target
Bcl-2-related protein A1
Ligand
BDBM33137
Substrate
n/a
Meas. Tech.
Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1
EC50
2320±n/a nM
Citation
 PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1 PubChem Bioassay (2009)[AID]
Target
Name:
Bcl-2-related protein A1
Synonyms:
B2LA1_HUMAN | BCL2A1 | BCL2L5 | BFL1 | Bcl-2-like protein 5 | GRS | HBPA1 | Hemopoietic-specific early response protein | Protein BFL-1 | Protein GRS
Type:
Apoptosis regulator protein
Mol. Mass.:
20130.01
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
175
Sequence:
MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC
  
Inhibitor
Name:
BDBM33137
Synonyms:
(5E)-3-ethyl-5-[(2E)-2-(1-ethyl-2-pyridinylidene)ethylidene]-2-sulfanylidene-4-thiazolidinone | (5E)-3-ethyl-5-[(2E)-2-(1-ethyl-2-pyridylidene)ethylidene]-2-thioxo-thiazolidin-4-one | (5E)-3-ethyl-5-[(2E)-2-(1-ethylpyridin-2-ylidene)ethylidene]-2-sulfanylidene-1,3-thiazolidin-4-one | 3-ethyl-5-[2-(1-ethyl-2(1H)-pyridinylidene)ethylidene]-2-thioxo-1,3-thiazolidin-4-one | MLS000699910 | SMR000225150 | cid_5846425
Type:
Small organic molecule
Emp. Form.:
C14H16N2OS2
Mol. Mass.:
292.42
SMILES:
CCN1C(=S)S\C(=C\C=C2/C=CC=CN2CC)C1=O |c:10,12|
Structure:
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