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Target
2'-phosphotransferase
Ligand
BDBM55012
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1).
IC50
>55688±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). PubChem Bioassay (2009)[AID]
Target
Name:
2'-phosphotransferase
Synonyms:
likely tRNA 2'-phosphotransferase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23631.37
Organism:
Candida albicans SC5314
Description:
gi_68476498
Residue:
207
Sequence:
MPPPDKARRDVLISKALSYLLRHGAEKEKLSIDDQGYVKISDVLSHQRLKSLKTTRDDINRIVQENDKKRFTIKDDMICANQGHSLKAVKNDNLTPMTVDELNQLRIYHGTYRTKLPLIKSSGGLSKMNRNHIHFTCEQYSTCSGIRYNANVLIYINASKCIEHGIVFYKSLNNVILTSGDKDGKLSWEFIDRIVGLDGNEINKEQV
  
Inhibitor
Name:
BDBM55012
Synonyms:
(5Z)-1-(2-furanylmethyl)-5-[[1-[2-(4-methylphenoxy)ethyl]-2-pyrrolyl]methylidene]-1,3-diazinane-2,4,6-trione | (5Z)-1-(2-furfuryl)-5-[[1-[2-(4-methylphenoxy)ethyl]pyrrol-2-yl]methylene]barbituric acid | (5Z)-1-(furan-2-ylmethyl)-5-[[1-[2-(4-methylphenoxy)ethyl]pyrrol-2-yl]methylidene]-1,3-diazinane-2,4,6-trione | 1-Furan-2-ylmethyl-5-[1-[1-(2-p-tolyloxy-ethyl)-1H-pyrrol-2-yl]-meth-(Z)-ylidene]-pyrimidine-2,4,6-trione | MLS000769050 | SMR000433820 | cid_1852376
Type:
Small organic molecule
Emp. Form.:
C23H21N3O5
Mol. Mass.:
419.4299
SMILES:
Cc1ccc(OCCn2cccc2\C=C2\C(=O)NC(=O)N(Cc3ccco3)C2=O)cc1
Structure:
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