Reaction Details  Report a problem with these data
Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62103
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
9468±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID]
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62103
Synonyms:
4-methyl-N-[2-(3-methyl-1,2-oxazol-5-yl)-1-phenyl-ethyl]aniline | 4-methyl-N-[2-(3-methyl-1,2-oxazol-5-yl)-1-phenylethyl]aniline | 4-methyl-N-[2-(3-methyl-5-isoxazolyl)-1-phenylethyl]aniline | MLS000699501 | SMR000230357 | [2-(3-methylisoxazol-5-yl)-1-phenyl-ethyl]-(p-tolyl)amine | cid_11842385
Type:
Small organic molecule
Emp. Form.:
C19H20N2O
Mol. Mass.:
292.3749
SMILES:
Cc1cc(CC(Nc2ccc(C)cc2)c2ccccc2)on1
Structure:
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