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Target
Neuropeptides B/W receptor type 1
Ligand
BDBM42453
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
14602±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID]
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM42453
Synonyms:
2-[2-(2-hydroxyethylamino)benzimidazol-1-yl]-N-[1-(2-norbornyl)ethyl]acetamide | MLS000516952 | N-[1-(3-bicyclo[2.2.1]heptanyl)ethyl]-2-[2-(2-hydroxyethylamino)-1-benzimidazolyl]acetamide | N-[1-(3-bicyclo[2.2.1]heptanyl)ethyl]-2-[2-(2-hydroxyethylamino)benzimidazol-1-yl]acetamide | N-[1-(3-bicyclo[2.2.1]heptanyl)ethyl]-2-[2-(2-hydroxyethylamino)benzimidazol-1-yl]ethanamide | SMR000343112 | cid_3983351
Type:
Small organic molecule
Emp. Form.:
C20H28N4O2
Mol. Mass.:
356.4619
SMILES:
[H]C12CCC([H])(C1)C(C2)C(C)NC(=O)Cn1c(NCCO)nc2ccccc12 |TLB:9:7:6:3.2|
Structure:
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