Reaction Details  Report a problem with these data
Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62128
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
14602±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID]
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62128
Synonyms:
5-(4-chlorophenyl)-N-(3-pyridinylmethyl)-2-(trifluoromethyl)-3-furamide | 5-(4-chlorophenyl)-N-(3-pyridinylmethyl)-2-(trifluoromethyl)-3-furancarboxamide | 5-(4-chlorophenyl)-N-(3-pyridylmethyl)-2-(trifluoromethyl)-3-furamide | 5-(4-chlorophenyl)-N-(pyridin-3-ylmethyl)-2-(trifluoromethyl)furan-3-carboxamide | MLS000830221 | SMR000458142 | cid_2810388
Type:
Small organic molecule
Emp. Form.:
C18H12ClF3N2O2
Mol. Mass.:
380.748
SMILES:
FC(F)(F)c1oc(cc1C(=O)NCc1cccnc1)-c1ccc(Cl)cc1
Structure:
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