Reaction Details  Report a problem with these data
Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62130
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
7845±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID]
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62130
Synonyms:
2-[({2-[(4-chlorobenzyl)oxy]-1-naphthyl}methyl)amino]-2-methyl-1-propanol | 2-[[2-(4-chlorobenzyl)oxy-1-naphthyl]methylamino]-2-methyl-propan-1-ol;hydrochloride | 2-[[2-[(4-chlorophenyl)methoxy]-1-naphthalenyl]methylamino]-2-methyl-1-propanol;hydrochloride | 2-[[2-[(4-chlorophenyl)methoxy]naphthalen-1-yl]methylamino]-2-methyl-propan-1-ol;hydrochloride | 2-[[2-[(4-chlorophenyl)methoxy]naphthalen-1-yl]methylamino]-2-methylpropan-1-ol;hydrochloride | MLS001178722 | SMR000477190 | cid_2949571
Type:
Small organic molecule
Emp. Form.:
C22H24ClNO2
Mol. Mass.:
369.884
SMILES:
CC(C)(CO)NCc1c(OCc2ccc(Cl)cc2)ccc2ccccc12
Structure:
Search PDB for entries with ligand similarity: