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Target
Female germline-specific tumor suppressor gld-1
Ligand
BDBM32001
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction
IC50
3513±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction PubChem Bioassay (2010)[AID]
Target
Name:
Female germline-specific tumor suppressor gld-1
Synonyms:
GLD1_CAEEL | defective in Germ Line Development family member (gld-1) | gld-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50591.33
Organism:
Caenorhabditis elegans
Description:
gi_17507875
Residue:
463
Sequence:
MPSCTTPTYGVSTQLESQSSESPSRSSVMTPTSLDGDNSPRKRFPIIDNVPADRWPSTRRDGWSSVRAPPPARLTLSTNNRHIMSPISSAYSQTPNSLLSPAMFNPKSRSIFSPTLPATPMSYGKSSMDKSLFSPTATEPIEVEATVEYLADLVKEKKHLTLFPHMFSNVERLLDDEIGRVRVALFQTEFPRVELPEPAGDMISITEKIYVPKNEYPDYNFVGRILGPRGMTAKQLEQDTGCKIMVRGKGSMRDKSKESAHRGKANWEHLEDDLHVLVQCEDTENRVHIKLQAALEQVKKLLIPAPEGTDELKRKQLMELAIINGTYRPMKSPNPARVMTAVPLLSPTPLRSSGPVLMSPTPGSGLPSTTFGGSILSPTLTASNLLGSNVFDYSLLSPSMFDSFSSLQLASDLTFPKYPTTTSFVNSFPGLFTSASSFANQTNTNVSPSGASPSASSVNNTSF
  
Inhibitor
Name:
BDBM32001
Synonyms:
7-Oxo-7H-benzo[e]perimidine-4-carboxylic acid | 7-ketobenzo[e]perimidine-4-carboxylic acid | 7-oxidanylidenebenzo[e]perimidine-4-carboxylic acid | 7-oxo-4-benzo[e]perimidinecarboxylic acid | 7-oxobenzo[e]perimidine-4-carboxylic acid | CHEMBL166209 | MLS000077061 | SMR000008738 | cid_72574
Type:
Small organic molecule
Emp. Form.:
C16H8N2O3
Mol. Mass.:
276.2463
SMILES:
OC(=O)c1ccc2C(=O)c3ccccc3-c3ncnc1c23
Structure:
Search PDB for entries with ligand similarity: