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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM78639
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm
IC50
7057±302 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay (2011)[AID]
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM78639
Synonyms:
2-[(4-nitrobenzyl)thio]-N'-(3,4,5-trimethoxybenzylidene)acetohydrazide | 2-[(4-nitrobenzyl)thio]-N-[(3,4,5-trimethoxybenzylidene)amino]acetamide | 2-[(4-nitrophenyl)methylsulfanyl]-N-[(3,4,5-trimethoxyphenyl)methylideneamino]acetamide | 2-[(4-nitrophenyl)methylsulfanyl]-N-[(3,4,5-trimethoxyphenyl)methylideneamino]ethanamide | 2-[(4-nitrophenyl)methylthio]-N-[(3,4,5-trimethoxyphenyl)methylideneamino]acetamide | MLS000575437 | SMR000184687 | cid_1381004
Type:
Small organic molecule
Emp. Form.:
C19H21N3O6S
Mol. Mass.:
419.452
SMILES:
COc1cc(C=NNC(=O)CSCc2ccc(cc2)[N+]([O-])=O)cc(OC)c1OC
Structure:
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