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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM79127
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm
IC50
11337±293 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay (2011)[AID]
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM79127
Synonyms:
MLS001129832 | N-ethyl-3-[(2-methoxyphenyl)sulfamoyl]-N-[2-oxidanylidene-2-(thiophen-2-ylmethylamino)ethyl]benzamide | N-ethyl-3-[(2-methoxyphenyl)sulfamoyl]-N-[2-oxo-2-(thiophen-2-ylmethylamino)ethyl]benzamide | N-ethyl-N-[2-keto-2-(2-thenylamino)ethyl]-3-[(2-methoxyphenyl)sulfamoyl]benzamide | SMR000711596 | cid_24819715
Type:
Small organic molecule
Emp. Form.:
C23H25N3O5S2
Mol. Mass.:
487.592
SMILES:
CCN(CC(=O)NCc1cccs1)C(=O)c1cccc(c1)S(=O)(=O)Nc1ccccc1OC
Structure:
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