Reaction Details  Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM38949
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
7970±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID]
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM38949
Synonyms:
4-methoxy-N-[(4-methyl-2-pyridyl)carbamoyl]benzamide | 4-methoxy-N-[(4-methylpyridin-2-yl)carbamoyl]benzamide | 4-methoxy-N-[[(4-methyl-2-pyridinyl)amino]-oxomethyl]benzamide | MLS000048748 | SMR000060445 | cid_1540545
Type:
Small organic molecule
Emp. Form.:
C15H15N3O3
Mol. Mass.:
285.2979
SMILES:
COc1ccc(cc1)C(=O)NC(=O)Nc1cc(C)ccn1
Structure:
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