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Target
Bcl-2-related protein A1
Ligand
BDBM78703
Substrate
n/a
Meas. Tech.
Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen
IC50
>20000±0 nM
Citation
 PubChem, PC Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen PubChem Bioassay (2011)[AID]
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM78703
Synonyms:
(2S)-2-[4-[(1R)-1-amino-2-hydroxy-ethyl]triazol-1-yl]-3-(1H-indol-2-yl)-1-piperazino-propan-1-one;hydrochloride | (2S)-2-[4-[(1R)-1-amino-2-hydroxyethyl]-1-triazolyl]-3-(1H-indol-2-yl)-1-(1-piperazinyl)-1-propanone;hydrochloride | (2S)-2-[4-[(1R)-1-amino-2-hydroxyethyl]triazol-1-yl]-3-(1H-indol-2-yl)-1-piperazin-1-ylpropan-1-one;hydrochloride | (2S)-2-[4-[(1R)-1-azanyl-2-oxidanyl-ethyl]-1,2,3-triazol-1-yl]-3-(1H-indol-2-yl)-1-piperazin-1-yl-propan-1-one;hydrochloride | CD-MONO-SW-DP | MLS000560545 | SMR000327458 | cid_16129541
Type:
Small organic molecule
Emp. Form.:
C19H25N7O2
Mol. Mass.:
383.4475
SMILES:
N[C@@H](CO)c1cn(nn1)[C@@H](Cc1cc2ccccc2[nH]1)C(=O)N1CCNCC1
Structure:
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