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Target
Tropomyosin alpha-1 chain
Ligand
BDBM79648
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
>71485±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID]
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM79648
Synonyms:
1-(4-hydroxy-1,1-diketo-thiolan-3-yl)-3-phenyl-urea | 1-(4-hydroxy-1,1-dioxo-3-thiolanyl)-3-phenylurea | 1-(4-hydroxy-1,1-dioxothiolan-3-yl)-3-phenylurea | 1-[4-oxidanyl-1,1-bis(oxidanylidene)thiolan-3-yl]-3-phenyl-urea | MLS000058796 | N-(4-hydroxy-1,1-dioxidotetrahydro-3-thienyl)-N'-phenylurea | SMR000069062 | cid_2831180
Type:
Small organic molecule
Emp. Form.:
C11H14N2O4S
Mol. Mass.:
270.305
SMILES:
OC1CS(=O)(=O)CC1NC(=O)Nc1ccccc1
Structure:
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