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Target
Tropomyosin alpha-1 chain
Ligand
BDBM79663
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
>71507±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID]
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM79663
Synonyms:
5-(4-Fluoro-benzylamino)-2-morpholin-4-yl-benzoic acid | 5-[(4-fluorobenzyl)amino]-2-morpholino-benzoic acid | 5-[(4-fluorophenyl)methylamino]-2-(4-morpholinyl)benzoic acid | 5-[(4-fluorophenyl)methylamino]-2-morpholin-4-yl-benzoic acid | 5-[(4-fluorophenyl)methylamino]-2-morpholin-4-ylbenzoic acid | MLS000552062 | SMR000145787 | cid_1941989
Type:
Small organic molecule
Emp. Form.:
C18H19FN2O3
Mol. Mass.:
330.3535
SMILES:
OC(=O)c1cc(NCc2ccc(F)cc2)ccc1N1CCOCC1
Structure:
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