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Target
Tropomyosin alpha-1 chain
Ligand
BDBM79714
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
>71550±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID]
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM79714
Synonyms:
(2-allyloxy-5-bromo-benzyl)-ethyl-amine;hydrochloride | MLS000679986 | N-[(5-bromanyl-2-prop-2-enoxy-phenyl)methyl]ethanamine;hydrochloride | N-[(5-bromo-2-prop-2-enoxyphenyl)methyl]ethanamine;hydrochloride | N-[2-(allyloxy)-5-bromobenzyl]ethanamine hydrochloride | SMR000296878 | cid_2983409
Type:
Small organic molecule
Emp. Form.:
C12H16BrNO
Mol. Mass.:
270.166
SMILES:
CCNCc1cc(Br)ccc1OCC=C
Structure:
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