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Target
Tropomyosin alpha-1 chain
Ligand
BDBM79716
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
>71462±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID]
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM79716
Synonyms:
4-[[1-(4-chloranyl-3-methyl-phenyl)sulfonylpiperidin-3-yl]carbonylamino]benzoic acid | 4-[[1-(4-chloro-3-methyl-phenyl)sulfonylnipecotoyl]amino]benzoic acid | 4-[[1-(4-chloro-3-methylphenyl)sulfonylpiperidine-3-carbonyl]amino]benzoic acid | 4-[[[1-(4-chloro-3-methylphenyl)sulfonyl-3-piperidinyl]-oxomethyl]amino]benzoic acid | MLS000716052 | SMR000277569 | cid_3230755
Type:
Small organic molecule
Emp. Form.:
C20H21ClN2O5S
Mol. Mass.:
436.909
SMILES:
Cc1cc(ccc1Cl)S(=O)(=O)N1CCCC(C1)C(=O)Nc1ccc(cc1)C(O)=O
Structure:
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