Reaction Details  Report a problem with these data
Target
Carboxypeptidase B
Ligand
BDBM81908
Substrate
n/a
Meas. Tech.
Inhibition Assay
Ki
3.5e+4±n/a nM
Citation
 Fernández, D; Avilés, FX; Vendrell, J Aromatic organic compounds as scaffolds for metallocarboxypeptidase inhibitor design. Chem Biol Drug Des 73:75-82 (2009) [PubMed]  Article
Target
Name:
Carboxypeptidase B
Synonyms:
CPB
Type:
Enzyme
Mol. Mass.:
48382.46
Organism:
Helicoverpa zea (Corn earworm moth) (Heliothis zea)
Description:
Q3T905
Residue:
429
Sequence:
MKFLLVLALCAVVYAKHEAYIGWKSYYVGVATDAQAKALEPLIQKYELDFLSHPTKSREGVVLVKPQHQAGFVQDIEAGGITYRIHADDVKRQLEFDDQLIEMQRMSSFTRTAGRQLPYDNYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDENKPVIFIDGGIHAREWISPPSVTWAIHKLVEDVTENDLLEKFDWILLPVVNPDGYKYTFTNERFWRKTRSTNNNPLSQICRGADGNRNFDFVWNSIGTSNSPCSDIYAGTSAFSEVETRVVRDILHEHLARMALYLTMHSFGSMILYPWGHDGSLSQNALGLHTVGVAMASVIQSNALPNFPPYTVGNSALVIGYYIAGSSEDYAHSIGVPLSYTYELPGLSSGWDGFHLPPQYIEQVCRETWEGIVVGARRAGDLFRK
  
Inhibitor
Name:
BDBM81908
Synonyms:
3-(5-((naphthalen-1-yloxy)methyl)-4-pheny-4H-1,2,4-triazol-3-ythio)propanoic acid, 8
Type:
Small organic molecule
Emp. Form.:
C22H19N3O3S
Mol. Mass.:
405.47
SMILES:
OC(=O)CCSc1nnc(COc2cccc3ccccc23)n1-c1ccccc1
Structure:
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