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Target
Type-1 angiotensin II receptor
Ligand
BDBM82273
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_1621
Citation
 Hegde, SS; Bonhaus, DW; Johnson, LG; Leung, E; Clark, RD; Eglen, RM RS 39604: a potent, selective and orally active 5-HT4 receptor antagonist. Br J Pharmacol 115:1087-95 (1995) [PubMed]  Article
Target
Name:
Type-1 angiotensin II receptor
Synonyms:
AGTR1 | ANGIOTENSIN AT1 | Agtr1.2 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40518.13
Organism:
Xenopus tropicalis
Description:
B3DLC0
Residue:
355
Sequence:
MLSNVSTGEVKCARSGMHNYIFITIPIIYSTIFVVGVFGNSLVVIVIYSYMKMKTVASIFLMNLALSDLCFVITLPLWAAYTAMHYHWPFGDFLCKLASTAITLNLYTTVFLLTCLSIDRYTAIVHPMKSRIRRTVMVARLTCVGIWVVAFLASLPSIIYRQIYIFPGTNQTVCALVYQSGQIYFTIGMSLVKNIVGFFIPFLIILTSYTLIGKTLKEVCRAQRARNDDIFKMIVAVVLLFFFCWIPHQVFTFLDVLIQMDVIQNCKIYDIVDTGMPITICIAYFNSCLNPFLYGFFGKNFRKHFLQLIKYLPPKMRSHASVSTKMSTASQRLSDTKYASNKISLQMTDKEEHCK
  
Inhibitor
Name:
BDBM82273
Synonyms:
CAS_167710-87-4 | RS 39604
Type:
Small organic molecule
Emp. Form.:
C26H36ClN3O6S
Mol. Mass.:
554.099
SMILES:
COc1cc(COc2cc(N)c(Cl)cc2C(=O)CCC2CCN(CCNS(C)(=O)=O)CC2)cc(OC)c1
Structure:
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