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Target
5-hydroxytryptamine receptor 2C
Ligand
BDBM29525
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_880
Citation
 Gale, JD; Grossman, CJ; Whitehead, JW; Oxford, AW; Bunce, KT; Humphrey, PP GR113808: a novel, selective antagonist with high affinity at the 5-HT4 receptor. Br J Pharmacol 111:332-8 (1994) [PubMed]  Article
Target
Name:
5-hydroxytryptamine receptor 2C
Synonyms:
5-HT2C | HTR2C
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51631.71
Organism:
PORCINE
Description:
K7GSR7
Residue:
457
Sequence:
MVNLRKAVHSFLVHLIGLLVWQCDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIILTIGGNILVIMAVSLEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISLGVSVPIPVIGLRDEDKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIHVLRRQALMLLRGHTEEPPGISLDFLKCCKRNTDEENAANPNQDLNPRRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKVYRRAFSNYLRCNYKADKKPPIRQIPRVAATALSGRELNVNIYRHTNEPVIKKADDNEPGIEMQVENLELPVNPSNVVSERISSV
  
Inhibitor
Name:
BDBM29525
Synonyms:
3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 113808 | [3H]GR113808
Type:
radiolabeled ligand
Emp. Form.:
C19H27N3O4S
Mol. Mass.:
393.5
SMILES:
Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12
Structure:
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