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Target
Sentrin-specific protease 8
Ligand
BDBM84024
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
21400±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID]
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84024
Synonyms:
MLS-0446106.0001 | N-(1,3-benzothiazol-2-yl)-4-methyl-2-thiophenecarboxamide | N-(1,3-benzothiazol-2-yl)-4-methyl-thiophene-2-carboxamide | N-(1,3-benzothiazol-2-yl)-4-methylthiophene-2-carboxamide | cid_49852524
Type:
Small organic molecule
Emp. Form.:
C13H10N2OS2
Mol. Mass.:
274.361
SMILES:
Cc1csc(c1)C(=O)Nc1nc2ccccc2s1
Structure:
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