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Target
Sentrin-specific protease 8
Ligand
BDBM84027
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
1220±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID]
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84027
Synonyms:
MLS-0446111.0001 | N-(1,3-benzothiazol-2-yl)-3-chloranyl-thiophene-2-carboxamide | N-(1,3-benzothiazol-2-yl)-3-chloro-2-thiophenecarboxamide | N-(1,3-benzothiazol-2-yl)-3-chloro-thiophene-2-carboxamide | N-(1,3-benzothiazol-2-yl)-3-chlorothiophene-2-carboxamide | cid_49852533
Type:
Small organic molecule
Emp. Form.:
C12H7ClN2OS2
Mol. Mass.:
294.78
SMILES:
Clc1ccsc1C(=O)Nc1nc2ccccc2s1
Structure:
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